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The tests are "exact", in the Monte-Carlo sense -- they can be made as accurate as desired by specifying enough random shuffles. PCP Pattern Classification Program -- a machine-learning program for supervised classification of patterns vectors of measurements. Supports interactive keyboard-driven menus and batch processing. An augmented Windows version Aug. EXE - For comparisons of two independent groups or samples. The current version number is 3.

EXE - For use in descriptive epidemiology including the appraisal of separate samples in comparative studies. EXE - Miscellaneous randomization, random sampling, adjustment of multiple-test p-values, appraisal of synergism, assessment of a scale, correlation-coefficient tools, large contingency tables, three-way tables, median polish and mean polish, appraisal of effect of unmeasured confounders.

EXE - Multiple logistic regression. The current version number is 1. EXE - For appraisal of differences and agreement between matched samples or observations. EXE - Multiple Poisson regression. EXE - An expression evaluator with storage of constants, interim results, and formulae and calculator for p values and their inverse , confidence intervals, and time spans.

The current version number is 4. Provides sophisticated methods in a friendly interface. TETRAD is limited to models The TETRAD programs describe causal models in three distinct parts or stages: a picture, representing a directed graph specifying hypothetical causal relations among the variables; a specification of the family of probability distributions and kinds of parameters associated with the graphical model; and a specification of the numerical values of those parameters. EasySample -- a tool for statistical sampling. Supports several types of attribute and variable sampling and includes a random number generator and standard deviation calculator.

Has a consistent, easy-to-use interface. EpiData -- a comprehensive yet simple tool for documented data entry. Overall frequency tables codebook and listing of data included, but no statistical analysis tools. Calculate sample size required for a given confidence interval, or confidence interval for a given sample size. Can handle finite populations. Online calculator also available.

Grocer -- a free econometrics toolbox that runs under Scilab. It contains: most standard econometric capabilities: ordinary least squares, autocorelated models, instrumental variables, non linear least squares, limited dependent variables, robust methods, specification tests multicolinearity, autocorelation, heteroskedasticity, normality, predictive failure, It also contains some rare -and useful- features: a pc-gets device that performs automatic general to specific estimations, and a contributions device, that provides contributions of exogenous variables to an endogenous one for any dynamic equation.

Has a -rough- interface with Excel and unlike Gauss or Matlab, it deals with true timeseries objects. Deals with: preparing ecogeographical maps for use as input for ENFA e. Based on a new estimation method called Bound and Collapse. Developed within the Bayesian Knowledge Discovery project. See also the commercial product, called Bayesware Discoverer , available free for non-commercial use.

RoC: The Robust Bayesian Classi fier -- a computer program able to perform supervised Bayesian classification from incomplete databases, with no assumption about the pattern of missing data. Based on a new estimation method called Robust Bayesian Estimator. The program allows the user to repeatedly combine probabilities in series or in parallel, and at any time will show a trail of the calculations which led to the current probability value.

Other program capabilities are the calculation of probabilities from input data, Gaussian approximation, and the generation of a mean time between failure MTBF table for various levels of confidence. It is assumed that the user is familiar with the theory behind binomial probability distribution. Graphical displays include an automatic collection of elementary graphics corresponding to groups of rows or to columns in the data table, automatic k-table graphics and geographical mapping options, searching, zooming, selection of points, and display of data values on factor maps.

Simple and homogeneous user interface. Weibull Trend Toolkit -- Fits a Weibull distribution function like a normal distribution, but more flexible to a set of data points by matching the skewness of the data. Command-line interface versions available for major computer platform; a Windows version, WinBUGS, supports a graphical user interface, on-line monitoring and convergence diagnostics.

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Includes complete help files and sample networks. Bayesian Networks are encoded in an XML file format.

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StatCalc day free trial download -- a handy desk-top tool and instructional aid that transforms from a standard calculator to a collection of modules that calculate statistics, graph distributions, and provide statistical help with definitions, formulas, and interpretation. WinSPC day free trial -- statistical process control software to:. The Unscrambler -- multivariate data analysis software for exploratory statistics, regression analysis, classification, prediction, principal components analysis PCA , partial least squares regression PLSR analysis and three-way PLS regression and experimental design.

Free day evaluation copy available. Handles traditional single fixed sample designs, survival analyses, proportions, means, non-inferiority, flexible adaptive designs, group-sequential designs,? Free day limited-function trial version available for download. Statistics Problem Solver -- tutoring software that not only solves statistical problems, but also generates step-by-step solutions in order to help students understand how to solve statistical problems.

Graphs can be customized in color, scale, resolution, etc. Also calculates slope, area under the curve, tracing and matrix transformation. Calculus Problem Solver -- differentiates any arbitrary equation and outputs the result, providing detailed step-by-step solutions in a tutorial-like format. Can also initiate an interactive quiz in which you can solve differentiation while the computer corrects your solutions. Includes equivalence- and non-inferiority testing for most tests, Monte Carlo simulation for small samples; group sequential interim analyses.

Design-Ease and Design-Expert -- two programs from Stat-Ease that specialize in the design of experiments. Full-function day evaluation copies of both programs are available for download. AGREE -- to measure agreement of nominal data, where two or more judges classify objects into nominal scale categories.

Bayesware Discoverer -- a computer program able to learn Bayesian Belief Networks from possibly incomplete databases. This is a commercial product, available free for educational and other non-commercial use. ZeroRejects -- Implements the "Six Sigma" statistical process control methodology developed by Motorola. The alpha and beta version are freely downloadable. Prognosis -- for analysis of time-series data. Uuses artificial intelligence and powerful statistical methodology to achieve high forecasting accuracy.

Easy to use; does not require any background in statistics or time series analysis. Free evaluation copy available for download. Incredibly powerful and multi-featured program for data manipulation and analysis. Designed for econometrics, but useful in many other disciplines as well.

Compumine Rule Discovery System -- easy to use data mining software for developing high-quality rule based prediction models, such as classification and regression trees, rule sets and ensemble models. This program is licensed under the P3 license model wich means that it is free to use forever for developing rule-based predictive models, and can be freely downloaded here.

Creates output modelss as LaTeX files, in tabular or equation format. Has an integrated scripting language: enter commands either via the gui or via script, command loop structure for Monte Carlo simulations and iterative estimation procedures, GUI controller for fine-tuning Gnuplot graphs, Link to GNU R for further data analysis. Includes a sample US macro database. See also the gretl data page. Lets you create mathematical models, design and simulate experiments, and analyze data. Models can contain differential equations, which will be numerically integrated and fit to data.

Graphic and tabular output is provided. Includes normal fitting, Bayesian estimation, or simulation-only, with integrated or differential equation models. Allows selection of weighting schemes and methods for numerical integration. Free downloads for Macintosh and Windows; online manual, tutorial, sample data sets. JoinPoint Regression Program from the National Cancer Institute -- for the analysis of trends using joinpoint models where several different lines are connected together at the "joinpoints.

Takes trend data e. Models may incorporate estimated variation for each point e. In addition, the models may also be linear on the log of the response e. The software also allows viewing one graph for each joinpoint model, from the model with the minimum number of joinpoints to the model with maximum number of joinpoints. DTREG generates classification and regression decision trees. It uses V-fold cross-valication with pruning to generate the optimal size tree, and it uses surrogate splitters to handle missing data.

A free demonstration copy is available for download. NLREG performs general nonlinear regression. NLREG will fit a general function, whose form you specify, to a set of data values.

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NeuroSolutions -- applies neural network technology to many situations, including regression. Free evaluation version does everything except print or save networks. LOCFIT -- a software system for fitting curves and surfaces to data, using the local regression and likelihood methods. Origin -- technical graphics and data analysis software for Windows. CART -- Salford Systems flagship decision-tree software, combines an easy-to-use GUI with advanced features for data mining, data pre-processing and predictive modeling. Biostatistics and Epidemiology: Completely Free Anderson Statistical Software Library -- A large collection of free statistical software almost 70 programs!

Anderson Cancer Center. Two populations can be compared using direct and indirect standardization, the SMR and CMF and by comparing two lifetables. Confidence intervals and statistical test are provided. There is an extensive helpfile in which everything is explained. Sample Size for Microarray Experiments -- compute how many samples needed for a microarray experiment to find genes that are differentially expressed between two kinds of samples e.

Ideal for learning meta-analysis reproduces the data, calculations, and graphs of virtually all data sets from the most authoritative meta-analysis books, and lets you analyze your own data "by the book". Generates numerous plots: tandard and cumulative forest, p-value function, four funnel types, several funnel regression types, exclusion sensitivity, Galbraith, L'Abbe, Baujat, modeling sensitivity, and Trim-and-Fill.

This is a stand-alone Windows 95 through XP program that receives information about dose-limiting toxicities DLTs observed at some starting dose, and calculates the doses to be administered next. DLT information obtained at each dosing level guides the calculation of the next dose level.

Covers a wide variety of situations, including studies whose outcomes involve the Binomial, Poisson, Normal, and log-normal distributions, or are survival times or correlation coefficients. Epi InfoVersion 3. Epi Info has been in existence for over 20 years and is currently available for Microsoft Windows. The program allows for data entry and analysis. Within the analysis module, analytic routines include t-tests, ANOVA, nonparametric statistics, cross tabulations and stratification with estimates of odds ratios, risk ratios, and risk differences, logistic regression conditional and unconditional , survival analysis Kaplan Meier and Cox proportional hazard , and analysis of complex survey data.

Limited support is available. They can be downloaded individually , or as a single ZIP file. The calculation of person-years allows flexible stratification by sex, and self-defined and unrestricted calendar periods and age groups, and can lag person-years to account for latency periods. Developed by Eurostat to facilitate the application of these modern time series techniques to large-scale sets of time series and in the explicit consideration of the needs of production units in statistical institutes.

Contains two main modules: seasonal adjustment and trend estimation with an automated procedure e. Meta-analysis 5. Probably still the most frequently used meta-analysis software in the world. Can select the analysis of exact p values or effect sizes d or r, with a cluster size option. Can plot a stem-and-leaf display of correlation coefficients. A utility menu is provided that allows various transformations and preliminary computations that are typically required before the final meta-analysis can be performed. Developed to help physicians and medical researchers to synthesize evidence in clinical or therapeutic research.

Life Table -- available in Lotus and Excel formats. Uses age-specific mortality and morbidity data to convert relative risk estimates into absolute risk estimates. That is, it estimates the probability that a patient will suffer a specific morbid or mortal outcome in a given time interval. The user first specifies a data file that contains the needed mortality and morbidity data for the disease of interest.

She then gives her patient's age and relative risk, and the time interval over which the risk estimate is to be derived. The program derives this risk, which is given both interactively and in a log file. Surveys, Testing, and Measurement: Completely Free CCOUNT -- a package for market research data cleaning, manipulation, cross tabulation and data analysis. ProtoGenie -- a free extensible web-based environment for research design and data collection for surveys, experiments, clinical trials, time series, cognitive and vision research, and methods courses.

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Lets you specify groups and define measurement and treatment events and their sequencing. The goal is to let users move smoothly from research design and data collection to interim and final statistical analysis. Has a user-friendly interface to prepare command files, run the core estimation program, and display results. Allows different questionnaire items to have varying numbers of response categories useful when sparse responses require recoding into fewer response categories. Handles sporadically missing responses. Provides item fit statistics and diagnostic graphics of performance.

Rasch Measurement Software -- deals with the various nuances of constructing optimal rating scales from a number of usually dichotomous measurements, such as responses to questions in a survey or test. These may be freely downloaded, used, and distributed, and they do not expire. They are:. Q-Method -- a statistical program for analyzing data from the Q-Sort Technique. Enter data Q-Sorts the way they are collected, i. It computes intercorrelations among Q-Sorts, which are then factor-analysed with the Centroid or, alternatively, PCA method.

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Resulting factors can be rotated either analytically Varimax , or judgmentally with the help of two-dimensional plots. Finally, after selecting the relevant factors and 'flagging' the entries that define the factors, the analysis step produces an extensive report with a variety of tables on factor loadings, statement factor scores, discriminating statements for each of the factors as well as consensus statements across factors, etc. CSPro Census and Survey Processing System -- a public-domain software package for entering, tabulating and mapping census and survey data.

IMPS Integrated Microcomputer Processing System -- performs the major tasks in survey and census data processing: data entry, data editing, tabulation, data dissemination, statistical analysis and data capture control. Stats 2. SABRE -- for the statistical analysis of multi-process random effect response data.

Responses can be binary, ordinal, count and linear recurrent events; response sequences can be of different types. Such multi-process data is common in many research areas, e. Sabre has been used intensively on many longitudinal datasets surveys either with recurrent information collected over time or with a clustered sampling scheme. Windows versions available in Spanish and English. Mac, K; Win anticipated in September. Sociological Insights -- displays statistical information in an easy-to-use format, designed for teaching quantitative sociological reasoning.

It uses aggregate data from the 50 U. It uses questionnaire data from the and General Social Surveys to teach distribution and cross-tabulation. The States module has variables in all. AssiStat -- a Windows-based package of calculations and analyses useful in educational and psychological research, practice, and in measurement and statistics courses. Designed as a complement to typical statistical packages rather than as a primary analysis tool, it picks up where primary analysis packages usually fall short--in performing secondary analyses like correction of correlations for restriction in range or less-than-perfect reliability, and other specialized analyses and calculations usually not available in standard packages without special programming.

Free demo available. StatPac Survey Software -- to design andimplement surveys, and to acquire, manage and analyze data from surveys. Optional Web Survey Module and Advanced Statistics Module curve fitting, multiple regression, logistic regression, factor, analysis of variance, discriminant function, cluster, and canonical correlation. A demo version is available limited to 35 cases. NewMDSX -- software for Multidimensional Scaling MDS , a term that refers to a family of models where the structure in a set of data is represented graphically by the relationships between a set of points in a space.

MDS can be used on a variety of data, using different models and allowing different assumptions about the level of measurement. Analysis of brand choice, purchase frequency and preference data. ConTEST -- a decision support system for assembly of educational and psychological tests from item banks.

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T-Rasch -- exact or non-parametric tests for the Rasch model. Kwalitan -- for analysis of qualitative data, such as protocols of interviews, articles, and annual reports. This Excel spreadsheet converts confidence intervals to p values, and this PDF file explains it's background and use. Adds a new menu item and installs many powerful functions: matrix decompositions Cholesky, QR, singular values, LU , eigenanalysis eigenvalues and eigenvectors of square matrices and formulas for generation of random variables Normal, binomial, gamma, exponential, Poisson, logNormal.

Also has routines for iterating spreadsheets to run Monte Carlo simulations, conduct randomisation tests including the Mantel test and calculate bootstrap statistics. Some facilities for maximum-likelihood parameter estimation, and some other generally useful functions. Free download from website, which also has documentation, examples, and related links.

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RegressIt - An Excel add-in for teaching and applied work. Performs multivariate descriptive analysis and ordinary linear regression. Creates presentation-quality charts in native editable Excel format, intelligently formatted tables, high quality scatterplot matrices, parallel time series plots of many variables, summary statistics, and correlation matrices.

SimulAr -- Provides a very elegant point-and-click graphical interface that makes it easy to generate random variables correlated or uncorrelated from twenty different distributions, run Monte-Carlo simulations, and generate extensive tabulations and elegant graphical displays of the results. EZAnalyze -- enhances Excel Mac and PC by adding "point and click" functionality for analyzing data and creating graphs no formula entry required.

Does all basic "descriptive statistics" mean, median, standard deviation, and range , and "disaggregates" data breaks it down by categories , with results shown as tables or disaggregation graphs". Advanced features: correlation; one-sample, independent samples, and paired samples t-tests; chi square; and single factor ANOVA. Update Available! EZ-R Stats -- supports a variety of analytical techniques, such as: Benford's law, univariate stats, cross-tabs, histograms. Simplifies the analysis of large volumes of data, enhances audit planning by better characterizing data, identifies potential audit exceptions and facilitates reporting and analysis.

Marko Lucijanic's Excel spreadsheet to perform Log Rank test on survival data, and his article. SSC-Stat -- an Excel add-in designed to strengthen those areas where the spreadsheet package is already strong, principally in the areas of data management, graphics and descriptive statistics. SSC-Stat is especially useful for datasets in which there are columns indicating different groups.

Menu features within SSC-Stat can:. Each spreadsheet gives a graph of the distribution, along with the value of various parameters, for whatever shape and scale parameters you specify. You can also download a ZIP file containing all 22 spreadsheets. Sample-size calculator for cluster randomized controlled trials , which are used when the outcomes are not completely independent of each other.

This independence assumption is violated in cluster randomized trials because subjects within any one cluster are more likely to respond in a similar manner. A measure of this similarity is known as the intra-correlation coefficient ICC. Because of the lack of independence, sample sizes have to be increased. This web site contains two tools to aid the design of cluster trials — a database of ICCs and a sample size calculator along with instruction manuals. Very-high-precision Statistical Probability Functions -- Provides double-precision 16 significant figures mass , density, cumulative, inverse probability distributions, critical values, and confidence bounds for the geometric, negative binomial, binomial, Poisson, hypergeometric, negative hypergeometric, exponential, normal, chi-square, gamma, Student t, Fisher F and beta; non-central gamma, chi-square, beta, t and F; and the mixed Gamma-Poisson, Beta-Binomial, and Beta-Negative-binomial distributions.

The routines are programmed in VBA, embedded within an Excel spreadsheet that illustrates the usage of each of them. DE Histograms -- an Excel add-in that provides comprehensive descriptives stats, histograms, outlier detection, normality testing, and much more. Exact confidence intervals for samples from the Binomial and Poisson distributions -- an Excel spreadsheet with several built-in functions for calculating probabilities and confidence intervals.

Smith , of Virginia Tech. A user-friendly add-in for Excel to draw a biplot display a graph of row and column markers from data that forms a two-way table based on results from principal components analysis, correspondence analysis, canonical discriminant analysis, metric multidimensional scaling, redundancy analysis, canonical correlation analysis or canonical correspondence analysis. Allows for a variety of transformations of the data prior to the singular value decomposition and scaling of the markers following the decomposition. Formally validated to be "GMP" and "Part 11" compliant.

Free spreadsheets include:. A third spreadsheet concerns a method for two clusters by Donner and Klar. You will have to insert your own data by overwriting the tables in the second total number of positive responses and third total number of negative responses or fourth column total number. Demo's of spreadsheets include:. A free "lite" but still very powerful version for PC and Mac can be downloaded. Statistics -- executes programs written in the easy-to-learn Resampling Stats statistical simulation language. You write a short, simple program in the language, describing the process behind a probability or statistics problem.

Statistics then executes your Resampling Stats model thousands of times, each time with different random numbers or samples, keeping track of the results. When the program completes, you have your answer. Runs on Windows, Mac, Lunux -- any system that supports Java.

R -- a programming language and environment for statistical computing and graphics. Similar to S or S-plus will run most S code unchanged. Provides a wide variety of statistical linear and nonlinear modelling, classical statistical tests, time-series analysis, classification, clustering, Well-designed publication-quality plots can be produced, including mathematical symbols and formulae where needed.

The R environment includes:. RStudio -— is a set of integrated tools designed to help you be more productive with R. It includes a console, syntax-highlighting editor that supports direct code execution, as well as tools for plotting, history, debugging and workspace management. Integrated development environment Access RStudio locally Syntax highlighting, code completion, and smart indentation Execute R code directly from the source editor Quickly jump to function definitions Easily manage multiple working directories using projects Integrated R help and documentation Interactive debugger to diagnose and fix errors quickly Extensive package development tools RStudio Server Access via a web browser Move computation closer to the data Scale compute and RAM centrally Shiny A web application framework for R.

Turn your analyses into interactive web applications ILNumerics -- a numerical library for. NET that turns C into a 1st class mathematical language. It offers both scientists and software developers convenient syntax similar to Matlab , toolboxes for statistical functions and machine learning, high performance, wide platform support and 2D and 3D visualization features. There's a free "Community" edition and a pay-for "Professional" edition. Both have the same features and capabilities; they differ in how you would re-distribute them in your own software products.

Zelig -- an add-on for R that can estimate, help interpret, and present the results of a large range of statistical methods. It translates hard-to-interpret coefficients into quantities of interest; combines multiply imputed data sets to deal with missing data; automates bootstrapping for all models; uses sophisticated nonparametric matching commands which improve parametric procedures; allows one-line commands to run analyses in all designated strata; automates the creation of replication data files so that you or anyone else can replicate the results of your analyses hence satisfying the replication standard ; makes it easy to evaluate counterfactuals; and allows conditional population and superpopulation inferences.

It includes many specific methods, based on likelihood, frequentist, Bayesian, robust Bayesian, and nonparametric theories of inference. Zelig comes with detailed, self-contained documentation that minimizes startup costs for Zelig and R, automates graphics and summaries for all models, and, with only three simple commands required, generally makes the power of R accessible for all users. Zelig also works well for teaching, and is designed so that scholars can use the same program with students that they use for their research.

Apophenia -- a statistics library for C. Octave -- a high-level mathematical programming language, similar to MATLAB, for numerical computations -- solving common numerical linear algebra problems, finding the roots of nonlinear equations, integrating ordinary functions, manipulating polynomials, and integrating ordinary differential and differential-algebraic equations. Runs under Linux and Windows. J -- a modern, high-level, general-purpose, high-performance programming language.

J runs both as a GUI and in a console command line. J is particularly strong in the mathematical, statistical, and logical analysis of arrays of data. J systems have:. Matvec -- an object oriented programming language with extensive statistical capabilities. Can handle problems ranging from matrix and vector manipulation to the analysis of linear and generalized linear mixed models. OxMetrics -- an object-oriented matrix programming language with a comprehensive mathematical and statistical function library. Matrices can be used directly in expressions, for example to multiply two matrices, or to invert a matrix.

The major features of Ox are its speed, extensive library, and well-designed syntax, which leads to programs which are easier to maintain. Versions of Ox are available for many platforms. The "Console" version can be freely downloaded for academic and research use; the "Professional" version must be purchased. Many built-in fit fuctions for structural equation modeling and other statistical modeling. Useful for manipulating experimental data joining files, cleaning data, reformatting for input into other programs.

Computes basic statistics mean, std. Quickly and easily specify beliefs about quantities of interest, attach data to some or all of those quantities, and carry out the general process of Bayes linear adjustment. Produces interactive Bayes linear influence diagrams for the adjustments, providing simple graphical summaries of the adjustments and accompanying diagnostics.

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